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近来关于β受体阻滞剂对某些震颤有效的报告不少,引起了临床的注意,现简要介绍如下:帕金森氏病:Barcoft(1952), Constas(1962)报告帕金森氏病的震颤可因用肾上腺素而加重,用β受体阻滞剂对本病的震颤有效.Owen等发现在用肾上腺素以前先用β受体阻滞剂可使肾上腺素对震颤的增幅效果受到抑制,后来他们对16名帕金森氏病患者给予心得安90毫克/日,用交替双盲法,结果用药组比用安慰剂组震颤明显减轻.Abramsky将36名帕金森氏病患者分为两组,一组单用左旋多巴
Recent reports that beta blockers are effective for some tremor have attracted a great deal of clinical attention and are briefly described below: Parkinson’s Disease: Barcoft (1952), Constas (1962) report tremor in Parkinson’s disease May be due to the use of adrenaline and aggravate the use of β-blockers on the tremor of the disease effective.Owen and other found that the use of β-blockers before adrenaline can make epinephrine increase the inhibition of tremor, Later, they gave 16 patients with Parkinson’s disease propranolol 90mg / day, with an alternating double-blind method, the results of the treatment group than in the placebo group was significantly reduced tremor .Abramsky will be 36 patients with Parkinson’s disease are divided into two groups, A group of single levodopa