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本刊对氯喹合并周效磺胺或乙胺嘧啶(法西达)用于疟疾化学预防引起严重副作用已作过报道。本文进一步介绍旅游者服用氨酚喹啉作疟疾预防亦可引起不良反应,因而指出,迄今尚没有一种药物能十分满意地用于疟疾的化学预防。使用氨酚喹啉能引起中性粒细胞减少和颗粒性白细胞缺乏症,并有几例发生死亡。其不良反应发生率较高,约0.05％。考虑到此药的危险性,应十分小心使用。鉴于尚无药物能完全抑制疟疾的感染,因此疟疾预防主要应从减少人蚊接触方面进
This article has been reported on the use of chloroquine combined with psorafurone or pyrimethamine (Faridas) for the serious side effects of chemical prophylaxis against malaria. This article further describes that tourists taking paracetamol for malaria prevention may also cause adverse reactions and therefore points out that so far no single drug has been satisfactorily used for the chemical prevention of malaria. Armpitol can cause neutropenia and granulocytic leukemia, and in a few deaths. The incidence of adverse reactions higher, about 0.05%. Taking into account the dangers of this medicine, should be very careful to use. In view of the fact that no drug can completely suppress the infection of malaria, malaria prevention should mainly be directed at reducing contact with mosquitoes