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目的研究纳洛酮治疗脑干损伤的疗效,观察其不良反应。方法 38例脑干损伤患者,随机分为观察组和对照组,各19例。观察组采取常规治疗联合纳洛酮治疗,对照组采取常规治疗;观察两组脑干损伤患者的治疗情况,记录产生的不良反应。结果观察组中,有1例患者产生心跳速度过快的不良反应情况;观察组的总有效率84.2%高于对照组57.9%,差异有统计学意义(P<0.05)。结论纳洛酮治疗脑干损伤,安全性高,疗效显著,可在临床广泛应用。
Objective To study the curative effect of naloxone on brain stem injury and to observe its adverse reactions. Methods Thirty-eight patients with brain stem injury were randomly divided into observation group and control group, with 19 cases in each group. The observation group was treated with routine naloxone and the control group was treated routinely. The treatment of brain injury in both groups was observed and the adverse reactions were recorded. Results In the observation group, 1 patient had an adverse reaction of fasting heart rate. The total effective rate in the observation group was 84.2% higher than that in the control group (57.9%, P <0.05). Conclusion Naloxone treatment of brain stem injury, high safety, significant effect, can be widely used in clinical practice.