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目的分析颅脑损伤患者早期行神经节苷脂治疗的效果。方法 96例颅脑损伤患者,按随机数字表法分为观察组和对照组,每组48例。对照组行常规方法治疗,观察组在其基础上行神经节苷脂治疗,观察两组疗效。结果治疗10 d以后,两组患者重度类脑水肿均减少,颅内压均升高,且观察组的脑水肿与颅内压情况均优于对照组,观察组清醒时间(11.26±4.4)d比对照组(18.30±5.25)d早,且治疗后的3个月,格拉斯哥评分(GOS)均比对照组优,比较差异均具有统计学意义(P<0.05)。结论颅脑损伤患者早期行神经节苷脂治疗的效果显著,可在临床应用。
Objective To analyze the effect of ganglioside treatment in patients with craniocerebral injury in the early stage. Methods Ninety-six patients with craniocerebral injury were divided into observation group and control group according to random number table method, with 48 cases in each group. The control group was treated by conventional methods. The observation group was treated with ganglioside on the basis of the above, and the curative effect was observed. Results After 10 days of treatment, the severity of cerebral edema decreased and the intracranial pressure increased in both groups. The cerebral edema and intracranial pressure in the observation group were better than those in the control group. The awake time in the observation group (11.26 ± 4.4) d Compared with the control group (18.30 ± 5.25) d earlier than the control group, Glasgow score (GOS) was superior to the control group at 3 months after treatment. The differences were statistically significant (P <0.05). Conclusions The effect of ganglioside treatment in patients with craniocerebral injury at early stage is significant and can be used clinically.