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OBJ ECTIVE: To estimate whether echocardiography findings at the time of diag no sis of peripartum cardiomyopathy are predictive of persistent cardiac dysfunctio n. METHODS: Chart review of patients with peripartum cardiomyopathy between 1988 and 2001 was performed. Data from echocardiography, including fractional shorte ning and left ventricular end diastolic dimension, were recorded both at the tim e of diagnosis and at follow-up. Left ventricular dysfunction was defined by ec hocardiography as fractional shortening less than 30%and left ventricular end d iastolic dimension of 4.8 cm or more. RESULTS: Of 32 patients meeting our defini tion for peripartum cardiomyopathy and for whom follow-up data were available, 13 (41%) had recovery of ventricular function, while 19 (59%)continued to have persistent left ventricular dysfunction. Those who did not recover cardiac func tion had a higher left ventricular end diastolic dimension and a lower fractiona l shortening at diagnosis than those who recovered. A fractional shortening valu e less than 20%and a left ventricular end diastolic dimension 6 cm or greater a t the time of diagnosis was associated with a more than 3-fold higher risk for persistent left ventricular dysfunction. CONCLUSION: Along with being an importa nt diagnostic tool in peripartum cardiomyopathy, echocardiography may provide si gnificant prognostic information with regards to recovery of cardiac function.
OBJ ECTIVE: To estimate whether echocardiography findings at the time of diag no sis of peripartum cardiomyopathy are predictive of persistent cardiac dysfunctio n. METHODS: Chart review of patients with peripartum cardiomyopathy between 1988 and 2001 was performed. Data from echocardiography, including fractional shortening Left ventricular dysfunction was defined by ec hocardiography as fractional shortening less than 30% and left ventricular end d iastolic dimension of 4.8 cm or more. RESULTS: Of 32 patients meeting our defini tion for peripartum cardiomyopathy and for whom follow-up data were available, 13 (41%) had recovery of ventricular function, while 19 (59%) continued to have persistent left ventricular dysfunction. not recover cardiac func tion had a higher left ventricular end diastolic dimension and a lower fractiona l shortening at diagnosis than those who recovered. A fractional shortening valu e less than 20% and a left ventricular end diastolic dimension 6 cm or greater at the time of diagnosis was associated with a more than 3-fold higher risk for persistent left ventricular dysfunction. CONCLUSION: Along with being an importa nt diagnostic tool in peripartum cardiomyopathy, echocardiography may provide si gnificant prognostic information with regards to recovery of cardiac function.