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目的调查某医院外科病区围手术期患者抗菌药物使用的现状及合理性。方法对104例普外科患者围手术期抗菌药物应用进行回顾性分析。结果103例患者使用了抗菌药物,术前和术后使用抗菌药物的比例分别为37.9%和99.0%;头孢菌素类药物使用率最高,其次为硝基咪唑类、喹诺酮类。术后单用、二联、三联应用抗菌药物的比例分别为13.6%,52.4%,34.0%,手术后47.6%的患者用药时间>7d。结论在围手术期抗菌药物的使用中存在着不合理之处,应加强管理。
Objective To investigate the status and rationality of antimicrobial use in perioperative patients in a surgical ward of a hospital. Methods The clinical application of perioperative antibiotics in 104 cases of general surgery patients was retrospectively analyzed. Results Antimicrobial agents were used in 103 patients. The rates of preoperative and postoperative antibacterials were 37.9% and 99.0% respectively. The highest rates of cephalosporins were followed, followed by nitroimidazoles and quinolones. The rates of single, double and triple antibacterials were 13.6%, 52.4% and 34.0% respectively after operation, and 47.6% of the patients were treated for> 7 days. Conclusion There is an irrationality in the use of antimicrobial agents during perioperative period and management should be strengthened.