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目的:探讨不同时机应用抗生素治疗未足月胎膜早破对母婴结局的影响。方法:收集2015年11月至2016年11月收治的120例未足月胎膜早破孕妇,根据抗生素治疗时机不同分为2组,观察组<24h,对照组>24h,比较2组母婴结局。结果:观察组65例,宫内感染4例,占6.2%,产后出血6例,占9.2%,产褥感染3例,占4.6%;对照组55例,宫内感染23例,占41.8%,产后出血20例,占36.4%,产褥感染9例,占16.4%,组间差异显著(P>0.05)。观察组新生儿Apgar评分(9.3±0.2),对照组新生儿Apgar评分(6.5±0.1),组间差异显著(P>0.05)。结论:及时给予未足月胎膜早破者抗生素治疗,能有效改善母婴结局。
Objective: To investigate the different timing of antibiotic treatment of premature rupture of membranes on maternal and infant outcomes. Methods: 120 pregnant women with incomplete premature rupture of membranes who were treated from November 2015 to November 2016 were enrolled. According to the timing of antibiotic treatment, the patients were divided into two groups, the observation group <24h and the control group> 24h. ending. Results: The observation group of 65 cases, intrauterine infection in 4 cases, accounting for 6.2%, postpartum hemorrhage in 6 cases, accounting for 9.2%, 3 cases of puerperal infection, accounting for 4.6%; control group of 55 cases, intrauterine infection in 23 cases, accounting for 41.8% , 20 cases of postpartum hemorrhage, accounting for 36.4%, 9 cases of puerperal infection, accounting for 16.4%, significant difference between groups (P> 0.05). Apgar score (9.3 ± 0.2) and Apgar score (6.5 ± 0.1) in neonates in the observation group were significantly different between the two groups (P> 0.05). Conclusion: Timely administration of antibiotics to preterm premature rupture of membranes can effectively improve maternal and infant outcomes.