目前临床医学研究已表明偏头痛发生、发展与血流动力学改变及体内多种炎症递质存在有关.以往用药如(?)胺类衍生物. 阿司匹林、心得安等仅能拮抗其中部分因素,故疗效常不令人满意.我院1990～1992年间对44例偏头痛病人采用苯噻啶与消炎痛联合治疗,疗效满意,报道如下.1 资料与方法1.1 一般资料 44例中,男18例,女26例,年龄14～68岁.病程4个月～10年.典型偏头痛4例,普通型偏头痛38例,丛集性偏头痛2例.1.2 诊断标准①头痛周期性发作, 间歇期神经、精神状态正常;②可有先兆及阳性家族史;③病程3个月以上且多次发作;④发作期伴植物神经功能紊乱症状;⑤(?)除其它原因的头痛.1.3 临床表现 以一侧或双侧发作性搏动性头痛为特征,少数为刺痛与胀痛.与疲劳、天气变化.情绪紧张(?)眠等诱因有关者36例,与月经有关者8例;伴有纳差、恶心32例,呕吐20例,面色苍白或潮红16例,头晕7例,有先 At present, clinical studies have shown that the occurrence of migraine headache, development and hemodynamic changes and the body of a variety of inflammatory mediators exist in the past drug such as (?) Amine derivatives aspirin, propranolol, etc. can only antagonize some of these factors, So the effect is often not satisfactory in our hospital from 1990 to 1992, 44 migraine patients with PZT combined with indomethacin, with satisfactory results reported as follows.1 Materials and Methods 1.1 General Information 44 cases, 18 males , 26 females, aged 14 to 68. The course of 4 months to 10 years.Model migraine in 4 cases, 38 cases of common migraine, cluster migraine in 2 cases.1.2 diagnostic criteria ① headache periodic attack, intermittent Nerve, mental state is normal; ② may have a precursor and positive family history; ③ duration of more than 3 months and multiple seizures; ④ attack with autonomic dysfunction symptoms; ⑤ (?) Other causes of headache .1.3 clinical manifestations One or both episodes of episodic pulsatile headache is characterized by a small number of tingling and pain and fatigue, the weather changes. Emotional tension (?) Sleep induced other 36 patients, and menstrual related 8 patients; associated with satisfied 32 cases of nausea, vomiting in 20 cases, pale or flushing in 16 cases, Halo seven cases, the prior