人类应用药物已有几千年的历史，但是真正自觉地把安全性放在重要的位置，不过是近几十年的事。这是本世纪以来历次药害事件中，成千上万致残、致死换来的惨痛教训。80年代以来，由药物上市后的安全性监测研究发展形成一门新学科----药物流行病学（Pharmacoepidemiology）,是临 It has been thousands of years since human use of medicines, but truly consciously putting safety in the forefront is only a matter of decades. This is the painful lesson learned from thousands of mutilations and deaths that have taken place in the past few cases of phytosanitary measures since the beginning of this century. Since the 1980s, a new discipline has emerged since the listing of drug safety monitoring research (Pharmacoepidemiology)