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目的探讨影响岩斜区脑膜瘤(PCM)预后的相关因素。方法回顾分析解放军452医院2005年9月-2009年6月及四川大学华西医院1999年9月-2009年2月110例患者的临床资料及随访结果,通过单因素生存分析及Cox比例风险模型分析探讨影响PCM预后的相关因素。结果单因素生存分析发现8种相关因素影响PCM患者的预后,但Cox多因素分析仅发现脑干T2像高信号(OR=5.54,P=0.012)、肿瘤侵入脑干(OR=5.10,P=0.034)、病理高级别(OR=4.03,P=0.011)这3种因素有统计学意义。结论脑干T2像高信号、肿瘤侵入脑干、病理高级别可影响岩斜区脑膜瘤患者的预后。
Objective To explore the factors influencing the prognosis of petroclival meningioma (PCM). Methods The clinical data and follow-up results of 110 patients from 452 Hospital of People’s Liberation Army from September 2005 to June 2009 and West China Hospital of Sichuan University from September 1999 to February 2009 were retrospectively analyzed. Univariate survival analysis and Cox proportional hazards model To explore the factors that affect the prognosis of PCM. Results One-factor survival analysis found that 8 related factors affected the prognosis of patients with PCM, but Cox multivariate analysis showed only T2 signal hyperintensity (OR = 5.54, P = 0.012), tumor invasion of brain stem (OR = 5.10, 0.034). The three pathological factors (OR = 4.03, P = 0.011) were statistically significant. Conclusions High T2 signal of brain stem and tumor invading the brainstem may influence the prognosis of patients with petroclival meningioma.