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目前已在临床上广泛应用的降压药胍乙啶(guanethidine)——β-(N-氮八环)乙胍硫酸盐,能緩慢而持久地降低高血压,无神經节阻滞剂共有的副作用。在研究胍乙啶的結构与药理作用关系时
The widely used antihypertensive drug guanethidine, β-N- (N-octacyclohexyl) guanidine sulphate, which has been widely used in clinic, can slowly and persistently reduce the high blood pressure without ganglion blocker side effect. In the study of guanethidine structure and pharmacological effects