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钙(Ⅱ)是生物体内重要的金属离子,它与蛋白质结合主要以静电结合为主,它会与蛋白质中的羧基、羟基、肽键及酚基等发生相互作用。由于在远紫外区才能观察到其电子跃迁这一实验上的困难,使得钙(Ⅱ)-蛋白质结合的直接研究受到了很大的限制。稀土离子与钙(Ⅱ)有极为相近的离子半径,它们的成键性质与钙(Ⅱ)很相似,大都具有闭壳层的电子结构,主要通过静电相互作用与配体结合,且成键强度直接与离子半径有关系。因此研究稀土离子与蛋白质的基本结构单元——氨基酸的相互作用,对于理解生物体系中钙(Ⅱ)的成键性质
Calcium (Ⅱ) is an important metal ion in the body. It binds mainly to the protein mainly in the form of electrostatic bonds. It interacts with carboxyl, hydroxyl, peptide bonds and phenol groups in proteins. Direct experimental studies of calcium (II) -protein binding have been severely limited by the experimental difficulties in observing the electron transition in the far ultraviolet region. The rare earth ions and calcium (Ⅱ) have very similar ionic radii. Their bonding properties are similar to those of calcium (Ⅱ), and most of them have closed-shell electronic structures and are mainly bound to ligands by electrostatic interaction. Directly related to the ionic radius. Therefore, the study of rare earth ions and the basic structural unit of protein - amino acid interaction, understanding of the biological system of calcium (II) bonding properties