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目的 探讨蒙古族高血压的家庭聚集性及遗传和环境的相对作用。方法 对现场内的研究对象进行血压测量及家系调查 ,描绘家系谱图。用二项分布拟合优度 χ2 检验方法及相关分析法分析高血压的家庭聚集性及家庭内各成员间的血压相关性。结果 蒙古族高血压的分布不呈二项分布 ,存在着家庭聚集现象 ;家庭各成员间血压都具有显著性相关 ,其中同胞间的相关系数最高 ,同胞间收缩压与舒张压的相关系数分别为 0 38和 0 32。按妻子年龄分层后 ,分析夫妻间的血压相关性 ,只有妻子年龄≥ 5 0岁的夫妻血压有显著性差异。结论 蒙古族高血压存在着家庭聚集性 ,这种聚集性是由遗传因素和环境因素共同作用所致
Objective To investigate the familial aggregation of Mongolian hypertension and the relative role of genetic and environmental factors. Methods Blood pressure measurement and pedigree investigation were conducted on the subjects in the field and pedigree diagrams were drawn. The binomial distribution goodness of fit χ2 test and correlation analysis were used to analyze the family aggregation of hypertension and the blood pressure correlation among members of the family. Results The distribution of Mongolian hypertension did not show a binominal distribution, and there was a phenomenon of familial aggregation. There was a significant correlation between blood pressure among family members, with the highest correlation coefficient among siblings, and the correlation coefficients between sibling systolic pressure and diastolic pressure were 0 38 and 0 32. After stratified by age of wife, the correlation between husband and wife’s blood pressure was analyzed. Only the wife’s age was 50 years old. There was a significant difference in blood pressure between husband and wife. Conclusion There is familial aggregation in Mongolian hypertension, which is caused by the combination of genetic factors and environmental factors