目的:比较体型偏小患者与体型正常患者采用不同直径移植物重建前交叉韧带(ACL)的疗效。方法:选取2018年1月至12月期间南方医科大学第三附属医院关节/运动医学科行ACL重建术的63例患者资料。根据体型不同分为两组：观察组26例，男18例，女8例；年龄为（29.4±8.5）岁；患者身高较矮、体重较轻，应用的移植物直径为7.5 mm。对照组37例，男26例，女11例；年龄为（28.8±8.2）岁；患者体型正常，应用的移植物直径为8.0 mm。比较两组患者的失败率、患侧膝关节运动改变（以两组患者的正常膝关节为对照，共63侧）、等速肌力和Lysholm膝关节评分等。结果:两组患者身高、体重外其他一般资料及随访时间比较差异均无统计学意义（n P>0.05），具有可比性。对照组和观察组患者的失败率分别为2.7%（1/37）、3.8%（1/26），术后2年Lysholm膝关节评分分别为（86.6±10.1）、（90.2±6.9）分，差异均无统计学意义（n P>0.05）。观察组患者患侧膝关节的屈伸活动度[56.30°(51.10°，58.10°)]显著小于对照组患者[60.15°(58.95°，63.08°)]和正常膝关节[59.00°（56.45°，63.00°]，内外移位[7.30（5.30，8.30) mm]显著小于正常膝关节[9.00（7.00，12.00）mm]，外旋[0.97°(-1.59°，3.01°)]显著高于正常膝关节[-1.54°(-5.30°，2.28°)]，角速度60°/s时的伸膝肌力（65%±19%）显著小于对照组患者（78%±18%），差异均有统计学意义（n P0.05), indicating comparability between the 2 groups. In the control and observation groups, the failure rates were 2.7% (1/37) and 3.8% (1/26), and the Lysholm knee scores 2 years after surgery (86.6±10.1) points and (90.2±6.9) points, respectively, showing no statistical significance (n P>0.05). The range of flexion and extension was 56.30° (51.10°, 58.10°) in the observation group, significantly smaller than that in the control group [60.15°(58.95°, 63.08°)] and that for a normal knee joint [59.00° (56.45°, 63.00°]; the internal and external displacement in the observation group [7.30 (5.30, 8.30) mm] was significantly smaller than that for a normal knee joint [9.00 (7.00, 12.00) mm]; the external rotation in the observation group [0.97°(-1.59°, 3.01°)] was significantly larger than that for a normal knee joint [-1.54°(-5.30°, 2.28°)]; the knee extension muscle strength at 60°/s in the observation group was (65%±19%), significantly smaller than that in the control group (78%±18%) (alln P<0.05).n Conclusion:When small-sized and normal-sized patients use a 7.5 mm graft and a 8.0 mm graft respectively in ACL reconstruction, similar therapeutic outcomes can be expected.