近年来对心脏细胞起搏活动的离子流基础的解释有两个重要变化,一个是浦肯野纤维所谓的“起搏”电流IK_2,另一个是慢内向电流ISi。由于游离的单个细胞内压钳制(Isolated Single-cell、Votage Clamp)和膜片钳制(Patch Clamp)方法的应用使原来的技术发生了重大突破,人们得以将Isi分离成几个电流成份,并且用于记录到过去未引起足够重视的一 In recent years, there are two important changes in the explanation of the basal flow of cardiac pacing in cardiac cells. One is the so-called “pacing” current IK_2 of Purkinje fibers and the other is the slow inward current ISi. Due to a major breakthrough in the original technology due to the use of Isolated Single-Cell (Votage Clamp) and Patch Clamp methods, it was possible to separate Isi into several current components and use To record the past did not cause enough attention to one