论文部分内容阅读
血清、尿及体液中存在着人绒毛膜促性腺激素(hCG)的相关分子,可在妊娠、滋养层疾病、睾丸和卵巢生殖细胞肿瘤和某些非滋养层病的患者中检测到。但是,由于hCG相关分子在不同疾病中结构、大小和含量变化很大以及标本中的干扰物质,在用品牌hCG试验诊断和监测滋养层疾病时常产生假阴性或假阳性结果,造成漏诊或不必要的临床干预。综述hCG相关分子与滋养层疾病的关系和防止假阳性结果的方法。
Serum, urine and body fluids are associated with human chorionic gonadotropin (hCG) -related molecules that can be detected in patients with pregnancy, trophoblastic disease, testicular and ovarian germ cell tumors, and certain non-trophoblastic diseases. However, hCG-related molecules vary widely in structure, size, and content in different diseases, as well as interfering substances in specimens, often resulting in false-negative or false-positive results in the diagnosis and monitoring of trophoblastic diseases by the brand hCG test, resulting in misdiagnosis or unnecessary Clinical intervention. Overview of hCG related molecules and trophoblastic disease and prevent false positive results of the method.