雄性BN躯干部皮肤移植物,其郎格罕氏细胞(LC)以MHC不相容的雌性Lewis的LC更换后,在雌性BN上的存活期比内含雌性BN的LC的雄性BN躯干部皮肤移植物延长。有证据显示,这些移植物所具有的这种特点,是MHC限制性的结果。例如,将雄性BN躯干部皮肤移植物内原有的LC以MHC相容的雌性lew·1N的LC更换后,对移植物在雌性BN上的存活期并无影响。还有证据显示,缺乏MHC相容的LC的H-Y不相容性移植物,能引起对H-Y的耐受。 Male BN torso skin graft, whose Langerhans cells (LCs) were replaced with LCs of MHC incompatible female Lewis Lewis, had a longer survival on female BN than male BN trunk skin containing LC of female BN Extensions of the graft. There is evidence that these features of these grafts are a result of MHC confinement. For example, replacing the original LC in the male BN dermal graft with the MHC-compatible LC of female lew.1N had no effect on the graft survival on female BN. There is also evidence that H-Y incompatible grafts lacking MHC-compatible LC can elicit tolerance to H-Y.