呼吸道及肺局部的体液免疫反应是以IgA为中心而进行的。Humphrey等的实验证明,呼吸道及肺是一个产生抗体的器官,而其淋巴组织是产生抗体的基础,支气管有关的淋巴样组织及其所属淋巴结是呼吸道及肺局部免疫反应的中心环节。呼吸道局部产生的抗体大部分分泌到呼吸道内,一部分也可通过淋巴管进入血液。当肺疾病时,各种体液免疫因子可在血流和肺泡腔之间自由出入。所以为了掌握呼吸道及肺部疾病的体液免疫状态,对呼吸道、肺冲洗液和血清二者都需进行分析。呼吸道与消化道一样作为免疫器官,能对侵入 The humoral immune response to the respiratory and local lungs is centered on IgA. Experiments by Humphrey et al. Have shown that the respiratory tract and lungs are organs that produce antibodies, and that their lymphoid tissue is the basis for antibody production. Bronchial lymphoid tissues and their associated lymph nodes are central to local immune responses in the respiratory tract and lung. The majority of antibodies produced locally in the respiratory tract are secreted into the respiratory tract and some can enter the bloodstream through lymphatic vessels. When lung disease, a variety of humoral immune factors in the bloodstream and alveolar free access. Therefore, to understand the humoral immune status of respiratory and pulmonary diseases, both the respiratory tract, lung washings, and serum should be analyzed. Respiratory and digestive tract as an immune organ, can be invasive