一、前言由于化合物类型5和10具有生物活性,从而在药理上引起兴趣。因此,我们在进行全合成甾体的基础上,合成了这一类化合物,目的也是为了进一步开拓新的有效的合成途径。迄今,在制备化合物5的已知方法中,以Velluz等和Perelmann等所提供的方法占重要地位。化合物10可按Velluz等的全合成方法或从7a起始通过半合成制得。为此,我们采用了电化学方法,因它对药物的合成具有一定的吸引力。在电化学反应中,某些情况下发现有一 I. INTRODUCTION As compound types 5 and 10 have biological activity, they are of interest in pharmacology. Therefore, we synthesized this class of compounds on the basis of fully synthetic steroids, the purpose is also to further open up new and effective synthetic route. Hitherto, the method provided by Velluz et al. And Perelmann et al. Plays an important role in the known method for preparing compound 5. Compound 10 can be prepared by the semi-synthesis of the fully synthetic method of Velluz et al. Or starting from 7a. For this reason, we have adopted the electrochemical method because of its attractiveness to the synthesis of the drug. In electrochemical reactions, one is found in some cases