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在正常或疾病情况下,人体内酸碱平衡的调节是一个颇为复杂的过程.迄今尚存很多争议性问题,近年国外多倾向于建立各种数学模型,以期揭示体内酸碱平衡的调节机制.本文将“顺应性”这一概念,引入到人体酸碱平衡调节的研究中,并观察了在代谢性酸中毒和代谢性碱中毒时,肺参与代偿调节的顺应性变化范围和变化幅度,为应用数学模型进一步深入探讨机体内复杂的酸碱平衡调节机制,提供新的研究途径和手段.
In normal or disease conditions, the regulation of acid-base balance in human body is a rather complex process, and many controversial issues remain. In recent years, many foreign countries tend to set up mathematical models in order to reveal the regulatory mechanism of acid-base balance In this paper, the concept of “compliance” was introduced into the study of the regulation of acid - base balance in the human body, and the scope and magnitude of the compliance of pulmonary involvement in compensatory regulation during metabolic acidosis and metabolic alkalosis , To further explore the complex mechanism of acid-base balance adjustment in the body of mathematical models and to provide new research approaches and means.