妊娠伴有癫痫的病人,在临床上值得重视的问题是发作不易控制,两者之间的相互影响以及癫痫及抗癫药对胎儿畸形的影响,本文对以上几个问题作一综述。一、妊娠对癫痫的影响:文献报道妊娠与癫痫的关系有两种情况:①妊娠前即有癫痫发作,②妊娠期与妊娠毒血症无关的第一次挛痉发作,约占25%。伴有原发性癫痫的妇女在妊娠期癫痫发作的频率是难以估计的,但癫痫发作频率的波动则是妊娠期的自然现象。早在1867年就有报道,认为妊娠对癫痫发作的频率有 Pregnancy associated with epilepsy in patients, the issue worth noting is clinically difficult to control the seizures, the interaction between the two as well as epilepsy and antiepileptic drugs on fetal malformations, the paper reviewed the above problems. First, the impact of pregnancy on epilepsy: The relationship between pregnancy and epilepsy reported in the literature there are two situations: ① seizure before pregnancy, ② gestation period and pregnancy induced sepsis episiotomy, accounting for about 25%. Women with essential epilepsy are seldom estimated to have seizures during pregnancy, but fluctuations in the frequency of seizures are a natural phenomenon during pregnancy. As early as 1867 there have been reports that the frequency of pregnancy with seizures have