论文部分内容阅读
目的：探讨血ＣＡ１２５测定对子宫肌腺病的诊断价值。方法：采用放射免疫方法对５５例子宫肌腺病（其中１６例术后１周复测）、２０例子宫肌瘤和２０例正常妇女血ＣＡ１２５水平进行测定。结果：３者ＣＡ１２５均值Ｍ（Ｑｌ～Ｑｕ）分别为１０２．１（５６．３～１８２．１）ｋＵ／Ｌ、３４．６（３３．７～４３．８）ｋＵ／Ｌ和３３．１（３２．７～３３．８）ｋＵ／Ｌ，３者间相互比较，差异均有极显著性（Ｐ均＜０．０１）。若以ＣＡ１２５＞５０ｋＵ／Ｌ为阳性，其阳性率３者分别为８０．０％、１０．０％和５．０％，肌腺病者ＣＡ１２５阳性率显著高于其他两者（Ｐ均＜０．００１）。肌腺病患者ＣＡ１２５水平，和子宫大小呈正相关（ｒ＝０．３３，Ｐ＜０．０５）；和未服药者相比，服用性激素药物者ＣＡ１２５水平较低（Ｐ＜０．０５）；手术前、后相比，术后１周的ＣＡ１２５水平明显下降（Ｐ＜０．０１）。结论：ＣＡ１２５测定对子宫肌腺病有明显的辅助诊断价值，而且有助于与子宫肌瘤的鉴别
Objective: To investigate the diagnostic value of serum CA125 in diagnosis of adenomyosis of the uterus. Methods: Radioimmunoassay was used to determine the level of serum CA125 in 55 cases of uterine adenomyosis (16 cases in one week after operation), 20 cases of uterine fibroids and 20 cases of normal women. Results: The mean M (Ql ~ Qu) of three CA125 were 102.1 (56.3 ~ 182.1) kU / L, 34.6 (33.7 ~ 43.8) kU / L and 33.1 ( 32.7 ~ 33.8) kU / L, the three were compared with each other, the differences were significant (P <0.01). The positive rate of CA125> 50kU / L was 80.0%, 10.0% and 5.0%, respectively. The positive rate of CA125 in patients with muscular adenosis was significantly higher than that in other two groups (all P <0 .001). The level of CA125 in patients with adenomyosis was positively correlated with the size of the uterus (r = 0.33, P <0.05). Compared with those without medication, the level of CA125 was lower (P <0.05) Compared with before and after, the level of CA125 in one week after operation decreased significantly (P <0.01). Conclusion: CA125 determination of uterine adenomyosis has a significant diagnostic value, but also help identify with uterine fibroids