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目的了解南县人民医院药品不良反应(ADR)的发生情况及其给患者造成的危害。方法对南县人民医院2005～2007年265例ADR报告进行分类统计分析。结果引起ADR的药物共有10类48个品种,其中抗微生物药居首位,其次为消化系统用药和心脑血管用药。合并用药占80例(30.19%),单一用药185例(69.81%);以静脉用药途径为主。主要的ADR类型为过敏反应,其次是消化系统损害、皮肤及附件损害等。结论应加强不易观察和慢性ADR的监测。
Objective To understand the incidence of adverse drug reactions (ADR) in Nanxian People’s Hospital and its harm to patients. Methods A total of 265 ADR cases in Nanxian People’s Hospital from 2005 to 2007 were classified and analyzed. Results There were 10 categories and 48 varieties of drugs that caused ADR, among which antimicrobials ranked first, followed by digestive system drugs and cardiovascular and cerebrovascular drugs. The combined medication accounted for 80 cases (30.19%), a single medication 185 cases (69.81%); the main route of intravenous medication. The main types of ADR are allergic reactions, followed by digestive system damage, skin and accessory damage and the like. Conclusions Hard-to-observe and chronic monitoring of ADR should be strengthened.