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为研究宫颈癌高剂量率腔内后装治疗最佳方案，在国内首建裸鼠人体宫颈场移植瘤，以此进行放疗效应、剂量率效应的实验研究。通过移植瘤放射后的生长延迟及ＦＣＭ检测，发现￣（６０）Ｃｏ高剂量率放射（１００ｃＧｙ／ｍｉｎ）与低剂量率放射（１．５ｃＧｙ／ｍｉｎ）的生物效应比，约为１：０．７左右。按此比率设计的方案，治疗６６０例宫颈癌，（与镭疗比较）发现临床与实验相符。从而建立了疗效高、反应低的高剂量率腔内后装治疗方法。
In order to study the best protocol of high dose rate cervical intracavitary afterloading treatment, we firstly transplanted human cervical tumor in nude mice in our country to study the effect of radiation and dose rate. The bioeffect ratio of ~ (60) Co high dose rate radiation (100cGy / min) and low dose rate radiation (1.5cGy / min) was about 1: 0 through the growth retardation and FCM detection after transplanted tumor. 7 or so. According to the ratio of the design of the program, treatment of 660 cases of cervical cancer, (compared with radium therapy) found clinical and experimental. To establish a high efficacy, low response rate of high dose rate intracavity afterloading treatment.