[方法]针对44%单嘧扑灭WP在推广中的药效不佳问题,探索最佳用药措施。采用正交试验方法,对施药剂量、整地质量等7个影响因素进行比较试验。[结果]影响44%单嘧扑灭WP除草效果最重要的因素是施药剂量,其次是灌溉水量、土壤墒情、整地质量等。[结论]确定了44%单嘧扑灭WP的优化方案:施药剂量1800 g/hm2、整地紧实、土壤含水量15%、药后不进行喷灌,药效持效期45 d,能有效防控谷田杂草,特别是双子叶杂草。 [Method] Aiming at the problem of poor efficacy of 44% monopylpyrazine WP in the promotion, explore the best medication. Orthogonal test method was used to compare and test seven influencing factors such as dose, soil preparation quality and so on. [Result] The most important factor that affected the weeding effect of WP with 44% monosulfuron was the application dose, followed by irrigation water, soil moisture, soil preparation and so on. [Conclusion] The optimization scheme of WP with 44% monosulfuron was determined. The application dosage was 1800 g / hm2, the soil preparation was tight and the soil water content was 15% Control valley weeds, especially dicotyledonous weeds.