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目的探讨过氟化碳液体（ｐｅｒｆｌｕｏｒｏｃａｒｂｏｎｌｉｑｕｉｄ，ＰＦＣＬ）在晶体及玻璃体视网膜手术（ｖｉｔｒｅ－ｏｒｅｔｉｎａｌｓｕｒｇｅｒｙ，ＶＲ术）中的应用价值。方法应用ＰＦＣＬ（法国产过氟萘烷，ｐｅｒｆｌｕｏｒｏｄｅｃｌｉｎ，纯度１００％，Ｃ１０Ｆ１８）治疗２例（２只眼）晶体脱位于玻璃体内，采用玻璃体切除，ＰＦＣＬ漂浮晶体于前房，再行常规的白内障摘除术。在ＶＲ术中应用ＰＦＣＬ治疗３７例（３７只眼）复杂性视网膜脱离（网脱）、２例（２只眼）外伤性网脱和１例增殖性糖尿病视网膜病变（ＰＤＲ），采用玻璃体切除、膜剥离、ＰＦＣＬ使用、气液交换、眼内激光、惰性气体（ＳＦ６、Ｃ３Ｆ８）及硅油眼内填充。结果晶体脱位２例，顺利取出，术后视力均较术前明显提高。ＶＲ术４０例，使用ＰＦＣＬ一次，近期（出院时）观察有效３５例（３５只眼，８７．５％），失败５例（５只眼，１２．５％）。视力与术前比较提高者２４眼（６４．９％），不变９眼（２４．３％），降低４眼（１７．１４％）。２７例随访时间为３～１１月（平均６．５月），有效２５只眼（９２．６％），视力≥０．０５，占４８％。结论ＰＦＣＬ可安全有效的治疗晶体脱位于玻璃体内，提高了ＶＲ术?
Objective To investigate the value of perfluorocarbon liquid (PFCL) in vitre-oretinalsurgery (VR). Methods Two cases (2 eyes) with PFCL (perfluorodeclin, purity 100%, C10F18) were treated with vitrectomy and vitrectomy. PFCL floating crystals were placed in the anterior chamber and followed by conventional cataract extraction Surgery. 37 cases (37 eyes) complicated with retinal detachment (net off), 2 cases (2 eyes) traumatic reticular detachment and 1 case of proliferative diabetic retinopathy (PDR) were treated with PFCL in VR. Vitrectomy, Membrane stripping, PFCL use, gas-liquid exchange, intraocular laser, inert gas (SF6, C3F8) and silicone oil intraocular filling. Results 2 cases of dislocation of the crystal were successfully removed and the postoperative visual acuity was significantly higher than that before operation. Forty patients underwent VR, one with PFCL, and 35 (35 eyes, 87.5%) in the short term (at discharge). Five patients (5 eyes, 12.5%) failed. There were 24 eyes (64.9%) with visual acuity and preoperative improvement, 9 eyes (24.3%) unchanged and 4 eyes (17.14%) with unchanged vision. Twenty-seven patients were followed up for 3-11 months (mean 6.5 months), effective 25 eyes (92.6%), visual acuity ≥ 0.05, accounting for 48%. Conclusion PFCL can be used safely and effectively to treat the dislocation of the lens in the vitreous and improve the VR technique.