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非类固醇抗炎药(NSAID)对 SLE 患者,特别是伴有活动性肾病时,可促使肾功能恶化。本文旨在对熙研究 NSAID 对肾功能正常或轻度减退的 SLE 患者的影响。病人和方法 16例 SLE 患者,3例因不能耐受消炎痛而退出研究;余13例,女性11例,男性2例,平均年龄35.7±8.8岁。病程平均为9.5±5.6年。8例作肾活检,其中 SLEⅣ型1例,Ⅲ型3例,Ⅱ型1例,仅有免疫荧光异常2例,正常1例。所有患者肾
Non-steroidal anti-inflammatory drugs (NSAIDs) on SLE patients, especially with active nephropathy, can promote renal dysfunction. This article aims to study the effects of NSAID on SLE patients with normal or mild renal dysfunction. Patients and Methods 16 patients with SLE, 3 patients were unable to tolerate indomethacin and withdraw from the study; more than 13 cases, 11 females, 2 males, mean age 35.7 ± 8.8 years. The average duration of disease was 9.5 ± 5.6 years. There were 8 cases of renal biopsy, including 1 case of SLE type Ⅳ, 3 cases of type Ⅲ and 1 case of type Ⅱ, only 2 cases of abnormal immunofluorescence and 1 case of normal. All patients with kidney