代谢综合征(MS)以中心性肥胖、糖尿病或糖耐量受损、高血压、血脂异常以及高尿酸血症等合并出现为主要特点,以胰岛素抵抗(IR)为共同病理生理基础的临床症候群。目前,学者普遍认为肥胖作为MS的主要始发因素,可诱导机体IR的发生,继而诱导机体葡萄糖耐受不良、高血压、血脂紊乱等症状的出现[1]。现就MS与脂肪细胞因子的认识进展综述如下。1脂联素脂联素(APN)是脂肪组织特异性分泌的一种 Metabolic syndrome (MS) is characterized by central obesity, impaired glucose tolerance or impaired glucose tolerance, hypertension, dyslipidemia and hyperuricaemia, and is characterized by insulin resistance (IR) as a common pathophysiological basis. At present, scholars generally believe that obesity, as the main origin of MS, can induce the occurrence of IR in the body and induce the appearance of symptoms such as glucose intolerance, hypertension and dyslipidemia in the body [1]. Now on the understanding of MS and adipocytokines are summarized below. 1 Adiponectin (APN) is a type of adipose tissue-specific secretion