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二巯丁二酸(静脉制剂为二巯丁二酸钠)是新中国成立后我国自主研发的具有国际影响的新药之一,由中国科学院上海药物研究所丁光生教授和他的学生梁猷毅教授开发,是一种低毒、广谱的重金属解毒剂。上世纪50年代,丁光生教授等率先报道其可用于治疗重金属中毒,此后,多个国家均报道二巯丁二酸对铜、铅、锑、汞和砷等重金属的促排作用显著。二巯丁二酸(钠)也是中国肝豆状核变性(HLD)
Dimercaptosuccinic acid (intravenous sodium dimercaptosuccinate) is one of the newly developed Chinese drugs with independent influence after the founding of People’s Republic of China. It is developed by Professor Ding Guangsheng, a professor of Shanghai Institute of Materia Medica, Chinese Academy of Sciences and his student Professor Liang Yiyi , Is a low toxicity, broad-spectrum heavy metal antidote. In the 1950s, Professor Ding Guangsheng first reported that it can be used to treat heavy metal poisoning. Since then, several countries have reported that dimercaptosuccinate has a significant effect on promoting the emission of heavy metals such as copper, lead, antimony, mercury and arsenic. Dimercaptosuccinate (sodium) is also a Chinese hepatolenticular degeneration (HLD)