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HBV是一种嗜肝组织病毒 ,HBV感染肝组织的第一步是需侵入肝细胞 ,然后才能在肝细胞内复制繁殖。前S1蛋白主要存在于血清中完整HBV表面。近些年来 ,关于HBV前S1蛋白和前S2 蛋白的研究较多 ,有很多新的认识。认为前S1和前S2 蛋白在HBV附着和入侵肝细胞的机制
HBV is a hepadnavirus. The first step in HBV infection of liver tissue is to invade hepatocytes and then replicate in hepatocytes. Pre-S1 protein is mainly present in the serum intact HBV surface. In recent years, many studies have been conducted on the pre-S1 and pre-S2 protein of HBV. There are many new understandings. The mechanism by which pre-S1 and pre-S2 proteins attach to and invade hepatocytes in HBV is believed