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对４２例１个月至１２岁健康儿童（Ｃ组）及９例２～１１岁Ｘ－连锁低磷性佝偻病（ＸＬＨＲ）患者，于治疗前后采用全自动生化分析仪测定其血钙（Ｃａ）、磷（Ｐ）、碱性磷酸酶（ＡＬＰ），并计算其钙磷乘积（Ｃａ×Ｐ）。将ＸＬＨＲ患儿分为Ａ、Ｂ两组，Ａ组采用传统治疗，主要给予中性磷酸盐合剂，辅以维生素Ｄ制剂不规则治疗；Ｂ组联合给予罗钙全［１，２５（ＯＨ）２Ｄ３］及磷酸盐合剂规则治疗；两组观察时间为３～１２个月。结果显示，Ａ、Ｂ组治疗前的血Ｃａ、Ｐ及Ｃａ×Ｐ均显著低于Ｃ组，ＡＬＰ显著高于Ｃ组（Ｐ＜０．００１），Ａ、Ｂ组间各项指标均无差异（Ｐ＞０．０５）。治疗后半个月，Ｂ组较Ａ组血Ｃａ、Ｐ及Ｃａ×Ｐ均显著升高（Ｐ分别＜０．０５、＜０．０１、＜０．００１），ＡＬＰ显著降低（Ｐ＜０．０５），且Ｂ组Ｘ线片示骨密度较Ａ组明显进步；治疗后３个月时，Ｂ组Ｃａ×Ｐ已达正常范围，而Ａ组最高值仅为２．５３［正常３．２～５．０］（ｍｍｏｌ／Ｌ）２。提示：①ＸＬＨＲ患儿较健康儿童钙磷乘积降低２～３倍，因此骨骼不能矿化；②罗钙全３０～４０ｎｇ／（ｋｇ·ｄ）及磷８０～１００ｍｇ／（ｋｇ·ｄ）治疗ＸＬＨＲ短期效果好，未出现副作用；③罗钙全的治疗机制可能为?
42 healthy children (C group) from one month to 12 years old and 9 X-linked hypophosphatemic rickets (XLHR) patients aged 2 to 11 years were measured before and after treatment by automatic biochemistry analyzer. , Phosphorus (P), alkaline phosphatase (ALP), and calculated the calcium and phosphorus product (Ca × P). The children with XLHR were divided into two groups A and B. The patients in group A were treated with traditional therapy and were given neutral phosphate, supplemented with irregular treatment of vitamin D. The group B was given Luo calcium [1,25 (OH) 2D3 ] And phosphate mixture rule treatment; two groups observed for 3 to 12 months. The results showed that the levels of Ca, P and Ca × P in group A and group B before treatment were significantly lower than those in group C and ALP was significantly higher than those in group C (P <0.001). There was no significant difference between group A and group B (P> 0.05). Half a month after treatment, the levels of Ca, P and Ca × P in group B were significantly higher than those in group A (P <0.05, <0.01, <0.001, P < 05). The bone mineral density of group B was significantly improved compared with that of group A. At 3 months after treatment, Ca × P in group B reached the normal range, while the highest in group A was only 2.53 [normal 3.2 ~ 5.0] (mmol / L) 2. Hint: (1) The calcium and phosphorus products in children with XLHR were reduced by 2 to 3 times compared with those in healthy children, so the bones could not be mineralized. (2) The treatment of XLHR with 30-40ng / (kg · d) of total calcium and 80-100mg / (kg · d) The effect is good, no side effects; ③ Luo calcium treatment mechanism may be?