近年来,有关甲状腺疾病与放射线的研究有了许多进展,现摘要简述如下。 基础研究 Miller等用X线照射试管内培养的甲状腺滤泡上皮细胞,并以乳腺上皮细胞及皮肤纤维母细胞作对照,结果表明甲状腺滤泡上皮细胞对放射线甚为敏感。一般认为,放射线可诱发甲状腺滤泡上皮细胞遗传物质的损害,并影响其修复,易使细胞坏死及向恶变转化,但其确切机理则不详。 In recent years, there have been many advances in research on thyroid diseases and radiation. The summary is summarized as follows. Basic research Miller and other X-ray irradiation in vitro cultured thyroid follicular epithelial cells, and to breast epithelial cells and skin fibroblasts as controls, the results show that thyroid follicular epithelial cells are very sensitive to radiation. Generally believed that radiation-induced thyroid follicular epithelial cells of genetic material damage, and affect their repair, easy to make the cell necrosis and malignant transformation, but the exact mechanism is unknown.