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目的研究上海市西南地区成人病毒感染性腹泻患者的病原学特点。方法采用逆转录荧光定量-PCR方法进行病毒检测。结果 539例腹泻标本中,检出病毒阳性212例,单种感染207例,双重感染5例。A组轮状病毒检出率为4.27%(23/539),B组轮状病毒检出率为0,C组轮状病毒检出率为0,诺如病毒Ⅱ型检出率为31.91%(172/539),诺如病毒Ⅰ型检出率为1.48%(8/539),星状病毒检出率为0.93%(5/539),扎如病毒检出率为1.29%(7/539),腺病毒检出率为0.37%(2/539)。除诺如病毒Ⅱ的检出率在年龄分组中差异有统计学意义(χ2=10.26,P<0.05)外,其余均无统计学意义。8种病毒的检出率在性别分组中差异均无统计学意义。结论上海市西南地区成人腹泻患者中,诺如病毒和轮状病毒为病毒感染的主要病原体。
Objective To study the etiological characteristics of adult virus-infected diarrhea patients in southwestern Shanghai. Methods RT-PCR was used to detect the virus. Results Among the 539 cases of diarrhea, 212 were positive for the virus, 207 for single infection and 5 for double infection. The detection rate of rotavirus in group A was 4.27% (23/539), the detection rate of rotavirus in group B was 0, the detection rate of rotavirus in group C was 0, the detection rate of norovirus type Ⅱ was 31.91% (172/539), the detection rate of norovirus was 1.48% (8/539), the detection rate of astrovirus was 0.93% (5/539), the detection rate of tetanus virus was 1.29% (7 / 539), adenovirus detection rate was 0.37% (2/539). In addition to the detection rate of Norovirus Ⅱ in the age group differences were statistically significant (χ2 = 10.26, P <0.05), the rest were not statistically significant. There was no significant difference in the detection rate of the eight viruses among the sex groups. Conclusion Norovirus and rotavirus are the main pathogens of viral infection in adult diarrhea patients in southwest of Shanghai.