目的探讨胃及十二指肠溃疡并毛霉菌感染临床病理特征。方法回顾性分析我院12年来在外检中发现胃及十二指肠溃疡1586例，其中并发毛霉菌感染92例，占5．8％，溃疡肉眼特征为一大、二深、三不整。病理组织学检查，找到毛霉菌菌丝。结果胃及十二指肠溃疡的存在是继发毛霉菌感染的病理基础。结论提出胃及十二指肠溃疡大、深、不整时，要警惕毛霉菌感染的可能，病理检查时也应对此有所考虑。 Objective To investigate the clinicopathological features of stomach and duodenal ulcer and mucormycosis. Methods A retrospective analysis of our hospital in the 12 years of detection of gastric and duodenal ulcer in 1586 cases, of which 92 cases were complicated by mold infection, accounting for 5.8%, ulcer gross features of a large, two deep, three irregular. Histopathological examination to find Mucormomycosis. Results The presence of gastric and duodenal ulcer was the pathological basis of secondary Mucormi infection. Conclusions The gastric and duodenal ulcer proposed large, deep, not whole, to be alert to the possibility of Mucormycosis, pathological examination should also be considered.