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目的观察奥曲肽对重症急性胰腺炎(SAP)的治疗作用。方法选择我院2002年1月至2005年10月的SAP患者58例,随机分为治疗组和对照组(各29例)进行分析。结果治疗组在腹痛缓解、腹部压痛消失、血白细胞计数、乳酸脱氢酶浓度降低、腹水消失及并发症的发生等方面均优于对照组。结论奥曲肽对改善SAP症状的作用肯定。在目前SAP没有特殊有效治疗的情况下,它可作为治疗SAP的首选药物。
Objective To observe the therapeutic effect of octreotide on severe acute pancreatitis (SAP). Methods 58 patients with SAP in our hospital from January 2002 to October 2005 were randomly divided into treatment group and control group (29 cases each). Results The treatment group was better than the control group in relieving abdominal pain, disappearance of abdominal tenderness, white blood cell count, decreased lactate dehydrogenase concentration, disappearance of ascites and complications. Conclusion The effect of octreotide on improving the symptoms of SAP is definite. It is the drug of choice for the treatment of SAP in the absence of any specific effective treatment of SAP.