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白血病抑制因子在哺乳动物妊娠早期中具有重要的生物学功能。胚源和母体白血病抑制因子可作为胚胎营养因子促进胚胎的发育；母体白血病抑制因子可能通过调节子宫接受性和／或激活胚泡从而启动胚泡着床。
Leukemia inhibitory factor has important biological function in early pregnancy of mammals. Embryonic and maternal leukemia inhibitory factors can promote the development of embryos as embryonic trophoblasts; maternal leukemia inhibitory factors may initiate blastocyst implantation by regulating uterine receptivity and / or activating blastocysts.