患者　男 ,2 6岁 ,因其妻习惯性流产 7次来院就诊。患者结婚 4年 ,其妻子孕 7次 ,均于 5 0～ 80天无诱因发生自然流产 ,后 3次经保胎治疗无效。其妻孕期无不良物质接触史及感染史。夫妇表型、智力正常 ,无其它疾病史 ,无烟酒嗜好 ,非近亲结婚。细胞遗传学检查 :取夫妇外周血淋 Male patient, 26 years old, because of his wife habitual abortion 7 times to the hospital. Patient was married for 4 years, his wife was pregnant 7 times, were induced spontaneous abortion in 50 ~ 80 days, after 3 times of childbirth treatment ineffective. His wife had no history of adverse drug exposure and history of infection. The couple phenotype, mental normal, no other history of the disease, non-alcoholic drinks and tobacco preferences, non-relatives get married. Cytogenetic examination: take the couple peripheral blood