本实验一次灌胃给予小鼠不同剂量(0、5、10和15mg/kg体重)氯化甲基汞,于染毒后第5、10和15天分别处死各组部分小鼠,检查其精子总数、形态及睾丸病理改变,实验结果表明,给予氯化甲基汞小鼠精子数目减少,精子畸形率增高,睾丸呈现不同程度的病理改变。该实验从形态学方面证实氯化甲基汞对小鼠雄性生殖细胞具有明显的毒性作用。 In this experiment, mice were given different doses (0, 5, 10, and 15 mg/kg body weight) of methylmercury chloride once by gavage, and each group of mice was sacrificed on the 5th, 10th, and 15th day after exposure, and sperm were examined. The total number, morphology, and pathological changes of the testis showed that the number of spermatozoa in mice given methylmercury chloride was reduced, the rate of sperm deformity was increased, and the testes exhibited different degrees of pathological changes. This experiment confirmed morphologically that methylmercury chloride has a significant toxic effect on mouse male germ cells.