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目的：对传统换血疗法进行改进，并使该技术在新生儿疾病中得到广泛应用。方法：采用肱动脉（股动脉）、头皮静脉作换出、换入途径，置换出体内２倍血量救治红细胞Ｇ－６－ＰＤ缺陷致高胆红素血症及胆红素脑病、新生儿败血症、新生儿溶血病。结果：术后总胆红素、间接胆红素分别下降了５７９６％和５８５４％（Ｐ＜００１），迅速改善了机体内环境。结论：改良同步换血疗法疗效好、副作用少、操作简便且经济，值得在临床推广应用。
OBJECTIVE: To improve traditional blood transfusion therapy and make it widely used in neonatal diseases. Methods: Brachial artery (femoral artery) and scalp vein were used for replacement and replacement. The blood volume of 2 times of blood volume was replaced by hyperbilirubinemia and bilirubin encephalopathy caused by G-6-PD deficient erythrocytes, Sepsis, neonatal hemolytic disease. Results: Total bilirubin and indirect bilirubin decreased 5796% and 5854% respectively after operation (P <001), which rapidly improved the internal environment. Conclusions: The improved synchronous blood exchange therapy has good curative effect, less side effects, simple and economical operation, and is worthy of clinical application.