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目的探讨经腹超声检查在评估Crohn’s病(CD)活动性中的价值。方法临床通过CD活动指数(CDAI)评估22例CD患者的活动性,分为活动期组及缓解期组,通过超声观察该22例患者病变部位、肠壁厚度、结构层次、回声情况及能量多普勒超声Limberg分型情况等,探讨超声在评估CD活动性中的应用价值。结果 22例CD患者分为19例活动期组及3例缓解期组,其中19例活动期患者肠壁均节段性增厚,最厚为16 mm,最薄为5.1 mm,平均厚度为(8.25±2.91)mm;增厚肠段肠壁层次消失的有17例,占89.5%(17/19);Limberg分级中Ⅲ级及以上有18例,占94.7%(18/19);而缓解期3例患者超声图像与活动期相比肠壁增厚不明显,平均厚度约(3.83±0.21)mm(与活动期肠壁厚度比较,P=0.018,<0.05),肠壁分层重新出现,但层次依然减少,并且Limberg分级均处于Ⅱ级(与活动期Limberg分型情况比较,P=0.000,<0.05)。结论 CD患者活动期与缓解期超声图像区别显著,经腹超声检查可作为评价CD活动性的方法之一。
Objective To investigate the value of transabdominal ultrasonography in assessing the activity of Crohn’s disease (CD). Methods The CD activity index (CDAI) was used to assess the activity of 22 patients with CD. The patients were divided into active group and remission group. The pathological changes, intestinal wall thickness, structure level, echogenicity and energy of the 22 patients Pulsed ultrasound Limberg classification, etc., to explore the value of ultrasound in the evaluation of CD activity. Results Twenty-two patients with CD were divided into two groups: active group (n = 19) and remission group (n = 3). The 19 patients with active stage had segmental thickening of the intestinal wall with a maximum thickness of 16 mm, a thinnest thickness of 5.1 mm and an average thickness of (8.25 ± 2.91) mm. There were 17 cases (89.5%) in the bowel wall of the thickening bowel, and there were 18 cases (grade Ⅲ and above) in the Limberg classification, accounting for 94.7% (18/19) Ultrasound images of patients showed no significant thickening of the intestinal wall compared with the active phase, with an average thickness of (3.83 ± 0.21) mm (P = 0.018, P <0.05) The levels were still reduced, and the Limberg grade was in grade II (P = .000, <.05 vs. Limberg classification in active stage). Conclusion There is a significant difference between the active and remission echocardiographic images in CD patients. Transabdominal ultrasonography can be used as one of the methods to evaluate CD activity.