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研究支气管剔除术对肺的形态结构和生理功能的影响。选用21只实验犬,分为七组。对照组3只,不施行任何手术:实验组6组,每组3只,分别于术后1周、2周、1月、3月、6月和12月取材,检测支气管肺泡灌洗液中肺表面活性物质的含量;肺组织标本进行透射电镜和光学显微镜观察。结果:术后接近被剔除支气管的肺组织呈创伤性反应,失去生理功能,但周边的广大肺组织结构正常,特别是6个月以后的远期表现良好。生化分析发现,术后两周内,PS含量显著增加(P<0.05),1月后与对照组相同(P>0.05)。提示支气管剔除术后的肺组织具有通气和换气功能。
To study the effects of bronchial removal on the morphology and physiology of lungs. 21 experimental dogs were selected and divided into seven groups. The control group of 3, without any surgery: experimental group 6, 3 in each group, respectively, after 1 week, 2 weeks, January, March, June and December were drawn, detection of bronchoalveolar lavage fluid Lung surfactant content; lung tissue specimens were observed by transmission electron microscopy and light microscopy. Results: The lung tissue near the bronchus removed was traumatic and lost physiological function. However, the surrounding lung tissue was normal, especially in the long term after 6 months. Biochemical analysis showed that within two weeks after surgery, PS content increased significantly (P <0.05), same as control group after 1 month (P> 0.05). Prompt bronchial resection of lung tissue with ventilation and ventilation function.