本文检测了４０例肾移植患者血清及尿液中ＴＮＦ的水平。结果发现血清标本中ＴＮＦ，４５例正常人对照组为０．６５±０．１０ｎｇ／Ｌ，３０例术后稳定组为０．９４±０．２１ｎｇ／Ｌ，７例发生急性排斥反应组为１．０３±０．２６ｎｇ／Ｌ。尿液中ＴＮＦ术后稳定组为０．４６±０．２９ｎｇ／Ｌ，排斥组为０．４４±０．３６ｎｇ／Ｌ。肾移植术后２ｄ血清及尿液ＴＮＦ水平开始增高，以后逐渐下降。连续动态检测对了解患者免疫状态、判断手术预后将有重要意义。 This article examines the serum and urine levels of TNF in 40 renal transplant recipients. The results showed that serum TNF, 45 cases of normal control group was 0.65 ± 0.10ng / L, 30 cases of stable group was 0.94 ± 0.21ng / L, 7 cases of acute rejection group was 1 .03 ± 0.26 ng / L. Urine TNF stabilized group was 0.46 ± 0.29ng / L, rejection group was 0.44 ± 0.36ng / L. After 2 days of renal transplantation, serum and urine TNF levels began to increase, and then gradually decreased. Continuous dynamic test to understand the patient’s immune status, to determine the prognosis of surgery will be of great significance.