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过敏性紫癜(HSP)是儿童一种较常见的系统性小血管炎,临床表现多样,以皮肤可触及的紫癜为主要症状。以胃肠道为主要症状的患者,临床主要表现为腹痛和消化道出血,其在皮肤紫癜出现前易误诊,误诊率可高达87.5%,治疗方面以早期应用糖皮质激素为主。现就HSP胃肠道症状的病因、发病机制、病理基础、临床表现、辅助检查和治疗的进展作一综述。
Henoch-Schonlein purpura (HSP) is a common form of systemic small vessel vasculitis in children. The clinical manifestations are diverse and the purpura, which is accessible to the skin, is the main symptom. Gastrointestinal tract as the main symptom of patients, the main clinical manifestations of abdominal pain and gastrointestinal bleeding, the skin is easy to misdiagnosis before the appearance of purpura, the misdiagnosis rate can be as high as 87.5%, the treatment of early glucocorticoid-based. Now on the etiology of HSP gastrointestinal symptoms, pathogenesis, pathology, clinical manifestations, laboratory examinations and treatment are reviewed.