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目的:比较活血类中药生药颗粒剂与生药材传统中药饮片的有效部位提取效能。方法:选择红花、桃仁及三七这三种活血类中药材作为研究对象,每种药材均分为生药材、传统中药饮片、中药生药颗粒,对3种药材的3个批次药物进行粗粉碎,提取总挥发油,计算每次所获取煎出物在总煎出物中所占百分率。结果:红花、桃仁及三七三种活血类药物的传统饮片与生药颗粒的有效部位煎出物在总煎出物中所占百分率均明显高于生药材,差异有统计学意义(P<0.05);有效部位煎出物在总煎出物中所占百分率与目数有明显关系,目数越高,其所占百分率也越高,24、50、65、80目组与10目组比较,差异均有统计学意义(P<0.05)。结论:红花、桃仁及三七等活血类中药生药颗粒剂及传统中药饮片有效部位提取效能均明显高于生药材,且粉碎目数越大,越利于有效成分的提取。
OBJECTIVE: To compare the extraction efficiencies of effective fractions of traditional Chinese medicine (Herbal medicine) tablets of Huoxue traditional Chinese medicine granules and raw herbs. Methods: Three Chinese medicinal materials, namely safflower, peach kernel and notoginseng, were selected as the research object. Each medicinal material was divided into raw herbs, traditional Chinese medicine slices and Chinese herbal medicine granule. Three batches of crude drugs Crush, extract the total volatile oil, calculate the percentage of the total amount of the decoction obtained in each time. Results: The percentages of the extract of safflower, peach kernel, and berberine three kinds of traditional Chinese medicine for promoting blood circulation were significantly higher than that of the crude drug (P <0.05) ; The effective part of the total amount of fried objects in the percentage of fried and the mesh has a clear relationship between the higher the number of heads, the higher the percentage of 24,50,65,80 mesh group and the 10-head group, The differences were statistically significant (P <0.05). CONCLUSION: The effective components of traditional Chinese medicine granules such as safflower, peach kernel, and notoginseng are significantly higher than those of crude drug. The larger the crushed mesh is, the easier the extraction of active ingredients.