莱姆病是一种蜱源性全身性疾病。由其病原体经血流至各组织、脏器引起病理改变，主要是非特异炎性浸润及免疫复合物损害所致。表现为多种多样的皮肤、关节、内脏、眼及神经系统病变。莱姆病转为慢性的机理是目前研究的焦点，可能与免疫逃避等因素有关 Lyme disease is a tick-borne systemic disease. By the pathogen of blood flow to various tissues, organs cause pathological changes, mainly due to non-specific inflammatory infiltration and damage caused by immune complexes. The performance of a wide range of skin, joints, internal organs, eye and nervous system diseases. The mechanism of Lyme disease becoming chronic is the focus of current research and may be related to immune evasion and other factors