临床资料 例1:患者女,60岁,因咳嗽、喘1周,于1994年10月24日来诊。既往有慢性支气管炎,曾反复应用青霉素、先锋霉素等抗菌素,无药物过敏及精神症状。否认精神或神经病史,家族中亦无精神病患者。查体:体温38℃,脉搏90次/分,呼吸20次/分,血压15/11kPa。发育正常,营养中等,神清合作。头、颈无异常,心、肺未见异常,腹软、肝脾未触及。神经系统检查未见异常。血、尿常规、肝肾功能检查及心电图均正常。X线拍片显示:双肺纹理走行紊乱,肺野透亮度增加,左下肺有斑片状阴影,诊断为慢性支气管炎继发感染,慢性阻塞性肺气肿。给予环丙氟哌酸(广州白云山制药总厂产乳酸环丙沙星)0.2g每日2次静脉点滴。用药后第2天体温降至正常,第3天出现多语、烦 Clinical data Example 1: Female patient, 60 years old, coughed and wheezy for 1 week, came to the clinic on October 24, 1994. Past chronic bronchitis, have repeatedly applied penicillin, cephalosporin and other antibiotics, no drug allergies and mental symptoms. Denied mental or neurological history, nor were psychiatric patients in the family. Physical examination: body temperature 38 ℃, pulse 90 beats / min, breathing 20 beats / min, blood pressure 15 / 11kPa. Normal development, moderate nutrition, clear cooperation. Head, neck, no abnormal heart, lung no abnormalities, abdominal soft, liver and spleen not touched. Nervous system examination showed no abnormalities. Blood, urine, liver and kidney function tests and ECG were normal. X-ray film showed: walk the lungs texture disorder, increased lung brightness, patchy shadow of the left lower lung, diagnosis of chronic bronchitis secondary infection, chronic obstructive pulmonary emphysema. Ciprofloxacin given (Guangzhou Baiyunshan Pharmaceutical Factory lactate ciprofloxacin lactate) 0.2g 2 times daily intravenous drip. On the second day after treatment, the body temperature dropped to normal, and the third day appeared in multiple languages, annoying