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麻风作为一种传染病,其病原菌与宿主间的关联,多数学者从各种角度进行了研究。晚近随着免疫学的进展,得到了进一步阐明,但是,仍有许多问题尚待探讨。作者认为目前在麻风中存在的问题是病型、病情变化及早期感染等。作者为阐明麻风感染机制,曾应用裸鼠及免疫抑制的Balb/c小鼠进行了动物实验,并进行了皮肤组织病理学观察。目前国际上普遍应用的并经世界卫生组织所推荐的麻风分型是Ridley-Jopling的5级分型(即LL BL-BB-BT TT 5型)。最近又加上一种接近LL的LI型,并认为各型可以相互演变。作者从冲绳、东南亚及日本全生园麻风院住院患者中选择了少数界线类患者进行了观察。抗酸菌染色法是用原田氏改良法。
Leprosy, as an infectious disease, the link between its pathogens and host, most scholars from various angles studied. With the recent progress of immunology, has been further clarified, however, there are still many issues to be explored. The author believes that the current problems in leprosy are the type of illness, the change of the disease and early infection. In order to elucidate the mechanism of leprosy infection, the authors conducted experiments in nude mice and Balb / c mice immunosuppressed, and observed the histopathology of the skin. Currently, Leprosy Typing, commonly used internationally and recommended by the World Health Organization, is Ridley-Jopling’s type 5 classification (ie LL BL-BB-BT TT 5). Recently, a type LI close to LL has also been added, and the various types can evolve with each other. The authors selected a small number of borderline patients from inpatient hospitalizations for leprosy in the whole Japanese Rana in Okinawa, Southeast Asia and Japan. Anti-acid bacteria staining method is Harada improvement method.