抗原和相应抗体结合所形成的复合物称为免疫复合物。在一般情况下,体内免疫反应产生的免疫复合物是有利的。例如病原体与相应抗体结合的复合物,更易被单核-巨噬细胞系统的细胞吞噬清除。又如细菌外毒素被相应抗毒素结合后,可中和其毒性。但在比例失调情况下,可出现免疫复合物病。近年来已发现的此类疾病至少有几十种。深入研究这些问题是当前免疫学的重要课题之一。 一、免疫复合物的形成和清除 免疫复合物的形成与抗原、抗体的性质、亲和性、比例,以及其周围环境的pH等有 Complexes formed by the binding of an antigen to a corresponding antibody are called immune complexes. In general, immune complexes produced by the immune response in the body are advantageous. For example, the complex of the pathogen with the corresponding antibody is more easily phagocytosed by the cells of the monocyte-macrophage system. Another example of bacterial exotoxin by the corresponding anti-toxin combined to neutralize its toxicity. However, in the case of imbalance, immunocomplex disease may occur. In recent years, there have been at least dozens of such diseases. In-depth study of these issues is one of the important topics in current immunology. First, the formation and clearance of immune complexes The formation of immune complexes and antigens, the nature of antibodies, affinity, ratio, and the pH of its surrounding there