发生振动病时,肌肉的代谢障碍具有重要意义。动物实验证实,振动作用下使参与肌肉氧化磷酸化过程的酶活性降低,肌肉组织发生肌酸——肌酸酐代谢障碍及营养障碍。正常人体内,高能磷酸衍生物——肌酸磷酸盐参与肌肉的能量代谢,并以肌酸酐的形式从尿中排泄。血和组织内的肌酸含量保持稳定水平,通常在 The occurrence of vibration sickness, muscle metabolic disorders are of great significance. Animal experiments confirmed that under the action of vibration to participate in the process of muscle oxidative phosphorylation decreased enzyme activity, muscle tissue creatine - creatinine metabolism disorders and nutritional disorders. Normal human body, high-energy phosphate derivatives - creatine phosphate involved in muscle energy metabolism, and in the form of creatinine excretion from the urine. Creatine levels in blood and tissues remain stable, usually at