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[目的]观察解郁安神汤联合艾司唑仑治疗肝郁化火失眠疗效。[方法]使用随机平行对照方法,将70例门诊患者按掷骰子方法简单随机分为两组。对照组35例艾司唑仑,1mg/次,1次/d,睡前口服。治疗组35例解郁安神汤,柴胡、龙胆草、栀子、生地各10g,当归8g,丹皮10g,合欢皮20g,生龙骨、生牡蛎各30g,郁金15g,香附10g,甘草8g,1剂/d,水煎200m L,2次/d;西药治疗同对照组。连续治疗28d为1疗程。观测临床症状、匹兹堡睡眠质量指数评分、不良反应。治疗1疗程(28d)。[结果]治疗组痊愈12例,显效17例,有效4例,无效2例,总有效率94.29%;对照组痊愈12例,显效11例,有效2例,无效10例,总有效率71.43%;治疗组疗效优于对照组(P<0.05)。匹兹堡睡眠质量指数评分两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]解郁安神汤联合艾司唑仑治疗肝郁化火失眠,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Jieyu Anshen Decoction combined with estazolam on liver depression and fire insomnia. [Methods] Using random parallel control method, 70 outpatients were randomly divided into two groups according to the method of dice rolling. Control group, 35 cases of eszolam, 1mg / time, 1 / d, before going to bed orally. Treatment group 35 cases of Jieyu Anshen soup, Bupleurum, gentian, gardenia, habitat the 10g, angelica 8g, Dan leather 10g, Albizia skin 20g, raw keel, raw oysters each 30g, turmeric 15g, incense attached 10g, Licorice 8g, 1 / d, decoction 200m L, 2 times / d; western medicine treatment with the control group. Continuous treatment 28d for a course of treatment. Observations of clinical symptoms, Pittsburgh Sleep Quality Index score, adverse reactions. Treatment of a course of treatment (28d). [Results] The treatment group cured 12 cases, markedly effective in 17 cases, effective in 4 cases, ineffective in 2 cases, the total effective rate was 94.29%; control group cured 12 cases, markedly effective in 11 cases, effective in 2 cases, ineffective in 10 cases, the total effective rate was 71.43% The treatment group was better than the control group (P <0.05). The Pittsburgh Sleep Quality Index score improved in both groups (P <0.05), and the treatment group improved better than the control group (P <0.05). [Conclusion] Jieyu Anshen Decoction combined with estazolam in the treatment of liver depression and fire insomnia has satisfactory curative effect and no serious adverse reactions, which deserves promotion.